C.B. Elias

Latest

• Recombinant protein production in large-scale agitated bioreactors using the baculovirus expression vector system
• Insights into the central metabolism of Spodoptera frugiperda (Sf-9) and Trichoplusia ni BTI-Tn-5B1-4 (Tn-5) insect cells by radiolabeling studies
• Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme
• Enhanced growth of Sf-9 cells to a maximum density of 5.2 x 107 cells per mL and production of β-galactosidase at high cell density by fed batch culture
• On-line monitoring of physiological parameters of insect cell cultures during the growth and infection process