process intensification

Intensification of influenza virus production in fed-batch and perfusion cultures of HEK293SF cells

More than half a million people die every year from complications of seasonal influenza, and vaccination stands as the most effective method to prevent and limit outbreaks of the disease. Constant vaccine development based on emerging strains and …

Recent advances and current challenges in process intensification of cell culture-based influenza virus vaccine manufacturing

Abstract Every year, millions of people are infected by the influenza virus around the world, which results in more than half a million deaths, particularly among the more vulnerable population. Since vaccination is the most efficient method of …