Project

Process development for the production and purification of rAAV based gene therapy vectors.

Skills

1. Mammalian and Insect cell culture
2. Glycoproteins production in rCHO cells
3. AAV vectorology
4. Analytical and Preparative chromatography
5. Molecular bioanalytics
6. Enzymology and Biocatalysis
7. Enzymatic biochemical reaction engineering

Work experience

Process development for the production of biotherapeutics including monoclonal antibodies (Bevacizumab) and hormones (FSH) in recombinant CHO cell line. Integral part of the scale-up team responsible for technology transfer to pilot and commercial scale facilities.

• 2013-2015: Associate Engineer in the Upstream Cell Culture group at Intas Pharmaceuticals Ltd., Biotechnology division (Ahmedabad, India)